1. Leptin regulates food intake
2. The pituitary gland is controlled by the hypothalamus and this gland has a molecule, PMOC which works through nerve types called Hypothalamic pro-opiomelanocortin (POMC) neurons which regulate energy and glucose metabolism. Leptin appears to work in part through stimulating these as well.
3. α-melanocyte stimulating hormone (α-MSH) is another hormone of weight control in the brain. Medically it is an anorexigenic factor: causing us eat less and store less body fat.
4.Another important molecule neuropeptide Y (NPY) is found in the brain and it is an "orexigenic" factor, is associated with promoting adipogenesis: fat generation
5. Peptide Yy, a little discussed molecule that is made in the small intestine and helps control our appetite by affecting the pancreas, and the mobility of the gut.