Your Chance of Getting Gynecologic Cancers: Update
1/8: Breast Cancer
1/38 Endometrial (uterine lining) Cancer
1/70 Ovarian Cancer
1/135 Cervical Cancer
By the way, a woman's risk of colon cancer is 1/25, just to put additional perspective on this. We have begun to slowly modify those risks based on certain other factors, just like smoking raises our lifetime risk of lung cancer, there are other associated factors that increase the risk of gynecologic cancers, such as the risk of cervical cancer greatly multiplies if you have a High Risk HPV virus infection.The newest trend was to begin to develop the genetic basis for some disease. BRCA1/2 genes can raise your risk of breast cancer a 50% or even 80% lifetime risk depending on your specific genetics. Although then having a mastectomy can lower that risk to virtually zero. If we can find the right gene, and 'correct' or edit the genes, the future of cancer control changes dramatically. The NIH wants to hone in on the genetics of cancers so that some of these clinical end points can be determined. Most cancers come from a defective gene operating at the tissue level. In most cases it develops over time, it's not specifically something you were born with. At the NIH there is a branch called the Cancer Genome Atlas Project trying to understand the genetics of over 20 common cancers. From this information it is hoped that the cancers can be either prevented or cured. Other branches of the international science community through the Summit on Gene Editing are supportive, but want us to establish important ethical guidelines, as well as open cooperation to make the technology available. There is a tremendous amount of research being published literally daily, and prevention is more than a dream, they seem to be around the corner.