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Monday, November 17, 2014

Uterine Fibroid Bleeding Can Be Controlled by Ulipristal Acetate in the PEARL 1 Trial

Medical therapies for shrinking fibroids have been shown that fibroid tumors and hormonally responsive and could shrink without surgery although both hysterectomies and myomectomies can control the bleeding from fibroids/ Women no longer want a hysterectomy or a myomectomy to control uterine fibroid bleeding, but if you have fibroids and heavy periods, and anemia, or pelvic pain, or pain with intercourse you probably need to gab with your gyno as it's important to get them treated. The amount of menstrual bleeding women experienced when they have both bleeding uterine fibroids and anemia has been published in what is call the PEARL I  research study of the selective progesterone receptor modulator (SPRM), ulipristal acetate (UPA). This medication can treat bleeding with fibroids, and is currently undergoing more research trials. In this first study, the fibroids were between 3 and 10 cm in size, and the uterus was no greater than a 16 week pregnant uterus. This first study did show significant promise with respect to uterine fibroid bleeding and a story we will follow closely.

ClinicalTrials.gov Identifier: NCT00755755 (PEARL I).

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