Teen PCOS Can Lead To Liver Disease That May Persist Into Adult Years.
To investigate the relationship between liver fat and in vivo insulin sensitivity, body composition, abdominal adiposity, and lipid metabolism in obese adolescent girls with polycystic ovary syndrome (PCOS). Liver fat deposits if allowed to go unchecked can lead to liver failure and difficulty processing medications and even difficulty with food, and also lead to more abnormal hormone levels and abnormal blood fat levels. Liver fat is directly associated with increasing age, even in the narrow adolescent age range, and the older one is the worse liver fat is. We find that girls and young women with PCOS have increasing abdominal adiposity, worsening insulin sensitivity, and dyslipoproteinemia and the more obese they are, the worse these conditions become. Targeting these abnormalities early in the course of PCOS may halt future nonalcoholic fatty liver disease in adulthood.The liver is the source for much of the detoxification of foods and medicines and it is important to maintain liver health as we age.