SSRIs and Female and Male Fertility

Since SSRIs, the most commonly used antidepressant medication class, affect sexuality, would they have an effect on fertility like ovulation or sperm counts? As for ovulation, no evidence shows that these medications directly influence ovulation, but if they increase the pituitary gland hormone prolactin, ovulation may adversely be affected.  Since men make so many extra sperm, and even fertile men may have highly variable sperm counts from week to week, so it's not really been possible to answer questions like this easily. Also those men experiencing a decrease in sexuality when on these medicines are less likely to have as much sex, which can of course affect the time a couple takes to conceive. So some physicians are proactively testing women and men who are on medication prior to attempts at conception so that the couple can plan alternatives such as insemination with the partner's sperm or at least timed intercourse that improves fertility rates. For women: ovulation tests, for men: semen analysis.Once you become pregnant there is some evidence that SSRI use is linked to miscarriages. It is not clear whether it is the conditon of depression that makes a woman prone to miscarry or if it's the fact of medication use itself.


  1. A bad move is to expose yourself to toxins and pro-oxidants. Don’t smoke, don’t drink, and don’t do drugs. This includes marijuana, which is proven to decrease male fertility.
    Good research work you have published on your blog. Sperm mobility count a lot in male febrility and you can have test of it. Medical procedure are advanced enough to cure infertility issues. Intra-cytoplasmic sperm injection is mostly widely using method these days for infertility caused by low mobility sperm count.


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