Fight Fat and Prevent Uterine Cancer

Uterine lining cancer, called endometrial cancer by gynos, has obesity as an established cause. Not only are you more likely to get uterine cancer if you are obese, you are more likely to die of that cancer.  as researchers form MD Anderson Cancer Center explain in a recent article in the American Journal of Obstetrics & Gynecology. Obese women have more estrogen. Their estrogen doesn't just come from their ovaries, but their estrogen comes from their fat, and the levels of estrogen in the fat are highly concentrated and greater than the levels we see in the blood stream! Obese women also have different hormones all together. They have less of the hormone binding substance called SHBG (serum hormone binding globulin) and with less of this substance the estrogen that they do have circulates free, thus is an effectively higher concentration. Estrogen promotes the growth of the uterine cancer cells itself. If you are a diabetic you are more prone to this uterine cancer, but if you are an obese diabetic, you are significantly more likely to get this cancer, as obesity promotes the production of insulin which in tern also signals cancer promoting cells growth. One of the fat regulating hormones, adiponectin changes when a woman is prediabetic or diabetic or what we call insulin resistant. We don't understand all the ways that hormones produced in our body fat affect conditions like lining cancer of the uterus, but current research supports that they do. So what specifically can women do: 1. use potent progesterone to counterbalance the effects of estrogen in the uterus, 2. take medicines that will improve your ability to respond to insulin, like the diabetic medicine glucophage, 3. loose weight, and 4. exercise which will change the amount of fat you have and the response to estrogen as well! So no one needs a better reason than these to get the fat off this new year!


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