Can We Cut PMS out of Us!?!
If we pose the question of what are the medical consequences of endometriosis. Most medical students will chime in: pain and infertility! and they would get a lot of credit, but the list goes on and on of the real medical consequences: from distorted tubal mobility, to alterations of the peritoneal fluid, to changes in immune system responses, like more autoantibodies, and we also have all sorts of havoc on the ovary itself. The ovary may not be able to form a normal follicle around the egg, it may not be able to release the egg, there is evidence it causes high production of the milk stimulating hormone prolactin (hyperprolactinemia), as well as luteal phase deficiencies. And with luteal phase deficiencies comes the production of abnormal luteal phase hormones and thus: Premenstrual Syndrome or Premenstrual Luteal Phase Dysphoria. We aren't completely sure of the link. Since the PMS/PMDD symptom complex occurs in the second half of the menstrual cycle, the part controlled by the corpus luteum of the ovary, it's thought there must be a link between the corpus luteum's function and endometrosis. LUF, or the syndrome of the corpus luteum forms before the follicle can rupture and release it's egg could be one of the reasons. So, if you suffer, and the endometriosis could be surgically treated, perhaps there is a way to actually cut the PMS out of us! Leave it to surgeons to find a novel way to use the knife!